本产品仅用于科研，不用于临床

英文名称 Anti-NMS/Neuromedin S
中文名称 神经调节肽S抗体
别 名 Neuromedin S; Neuromedin-S; Nms; NMS_HUMAN; Prepro NMS.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Dog
产品类型 一抗
研究领域 肿瘤 心血管 神经生物学 信号转导 生长因子和激素 新陈代谢
蛋白分子量 predicted molecular weight: 4kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neuromedin S
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 NMS is a 153 amino acid secreted protein that belongs to the NmU family. NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. The gene that encodes NMS consists of approximay 12,799 bases and maps to human chromosome 2q11.2. Consisting of 237 million bases and encoding over 1,400 genes, chromosome 2 makes up approximay 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.
Function : NMS （neuromedin S） is a 36-amino acid neuropeptide specifically expressed in the suprachiasmatic nucleus （SCN） of the hypothalamus. NMS shares a C-terminal core structure with NMU. NMS mRNA is highly expressed in the central nervous system, spleen and testis. NMS may be implicated in the regulation of circadian rhythms and feeding behavior.
Subcellular Location : Secreted
Similarity : Belongs to the NmU family.
Database links : UniProtKB/Swiss-Prot: Q5H8A3.1

宿主：Human、Murine、Rat （Rattus）、Bovine、Dog （Canine）等物种
神经调节肽S抗体应用范围: WB, ELISA, IP, IHC （p）, IHC （f）, IF
缓冲液：0.01m PBS,pH值7.4和10毫克/毫升BSA
储存液：0.1%（w/v）*          

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